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Rs1862416 was located within the boundaries of a genome-wide significant locus for smoking initiation (chr5:164,596,435-168,114,971), and to assess the independence of association signals at the single variant level, we performed conditional modeling using Genome-wide Complex Trait Analysis (GCTA) 40,41

Health Promotion Journal of Australia, 2022

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On the other hand, e-liquid allows for more control over nicotine intake due to the range of strengths available, making it hard to equate the two simply based on quantity